Chinese scientists have unveiled a groundbreaking medical adhesive named Bone-02, capable of repairing bone fractures in as little as three minutes, a feat that could transform orthopedic surgery. The project, led by Dr. Lin Xianfeng at Sir Run Run Shaw Hospital in Zhejiang Province, was inspired by oysters’ remarkable ability to cling firmly to wet, moving surfaces. Unlike traditional metal implants, Bone-02 is bioabsorbable, gradually dissolving as the bone naturally heals, eliminating the need for a second surgery to remove hardware. Tested successfully in over 150 patients, the adhesive has demonstrated impressive strength, safety, and rapid bonding even in blood-rich environments. Experts believe Bone-02 could dramatically reduce surgery time, lower infection risks, and accelerate recovery, marking a major breakthrough in fracture treatment worldwide.
Bone glue inspired by oysters
The development of Bone-02 is rooted in biomimicry, taking cues from how oysters withstand waves and water currents by adhering strongly to underwater surfaces. This adhesive mimics that natural resilience, giving surgeons a powerful tool to treat fractures in blood-rich environments where traditional adhesives often fail. Within two to three minutes of application, Bone-02 can secure broken bones with exceptional bonding force—measured at more than 400 pounds. Its quick action and durability offer surgeons greater efficiency and patients a smoother healing process.
Trials inspired confidence in results
Clinical trials of Bone-02 have already involved more than 150 patients, producing encouraging outcomes. Doctors reported that surgeries normally requiring steel plates and screws were completed in a fraction of the time. Beyond speed, the adhesive demonstrated robust physical properties, including a shear strength of 0.5 MPa and compressive strength of around 10 MPa, comparable to standard implants. Importantly, Bone-02 was well tolerated by the human body, showing no major safety concerns. These findings suggest it could eventually replace many traditional fixation methods in hospitals worldwide.
Inspired shift in fracture treatment
Bone-02’s bioabsorbable design means it naturally dissolves within about six months, disappearing as the bone regains strength. This eliminates the need for a second surgery to remove metal hardware, reducing both costs and recovery risks for patients. Orthopedic experts see this as a potential game-changer in fracture care, particularly in complex injuries or regions with limited access to advanced surgical facilities. If future trials continue to confirm its effectiveness, Bone-02 could lead to a paradigm shift in how fractures are treated—faster, safer, and more human-centered than ever before.
