The craving of non-food items such as ice, dirt, clay and paper, constitutes an unusual, yet significant indicator of iron deficiency known as pica. The most prevalent form of this condition leads people to seek ice, which they call pagophagia. Scientists have not identified the exact reason behind iron deficiency leading to pica, but they believe ice chewing might create temporary alertness in people with low iron levels. A person who experiences pica should seek medical evaluation, because their iron deficiency is severe and eating dangerous substances could result in harm.